The mission of the Multiple Sclerosis Research Institute (MSRI) is to perform the highest quality laboratory-based research and to provide outstanding education in the field of Multiple Sclerosis.
Multiple Sclerosis is a disease in which the body's immune system attacks the nervous system. The attacks cause an increasing degree of neurodegenerative damage over time allowing disease progression, and limiting the bodies ability to recover after each attack.
The research at MSRI focuses on developing a clearer understanding of fundamental mechanisms of the etiology and pathogenesis of MS. In addition, new therapeutic approaches to the disease and its complications are being carried out.
The basic laboratory research focuses on the following areas:
- Investigating regulation of the immune response and impairment of these responses which cause the occurrence of autoimmunity in MS. The major initial emphasis is placed on improving the understanding of the role of regulatory T cells in the etiology and pathogenesis of MS.
- Decoding the mechanisms by which an activated immune system causes damage to myelin and axons.
- Development of innovative therapeutic responses to treat MS.
- Development of diagnostic tests to diagnose and to monitor MS.
Educational programs to spread knowledge about the immune basis for MS, current research and therapeutic approaches have been developed for the following audiences:
- Specialists in MS research and care
- General neurologists
- Health Care Professionals
- Individuals with MS and their caregivers
A variety of forums are being used including:
- Small group meetings
Message from Dr. Greenstein
Curing MS is my life’s work. As you know, MS not only changes the lives of those affected by it, but it also touches the lives of their families and friends. My mission in founding the Multiple Sclerosis Research Institute (“MSRI”) is to FIND the cause, STOP the progression and CURE the disease so that those with MS, as well as future generations, can enjoy a life free from its symptoms.